Endocrine Abstracts

Background and Aims: Polycystic ovary syndrome (PCOS) usually develop symptoms during adolescence. However, diagnosis in adolescents is challenging because physiologic development overlap typical manifestation of PCOS. Recently, an international evidence-based PCOS guideline development group recommended that ultrasound should not be used for the diagnosis of PCOS in those with a gynecological age of < 8 years. Thus, girls with irregular menstruation (IM)/PCO or hyperandro...

Background and Aims: Anti-Müllerian hormone (AMH) is secreted by granulosa cells of ovarian follicles. Since AMH reflects the number of antral follicles and the pronounced androgen secretion from follicles/stroma in women with polycystic ovary syndrome (PCOS) remains until late reproductive age, the age related relationship between AMH in women with PCOS are of interest. Methods: Women with PCOS (aged 15–42 years) (n=537) participated ...

Background: Hirsutism, characterized by the male pattern distribution of terminal hair in females due to elevated androgen levels, is a diagnostic feature for polycystic ovary syndrome (PCOS), assessed by the modified Ferriman-Gallwey (mFG) score. The 2023 international PCOS guideline suggests an mFG score of 4-6 for hirsutism detection. However, the lack of universally applicable cut-offs in diverse populations necessitates further research. Therefore, this study aimed to def...